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VCAM1 (基因名), Vascular cell adhesion protein 1 (蛋白名), vcam1_human.
产品名称:

Human VCAM1/ Vascular cell adhesion protein 1 Recombinant Protein
血管细胞黏着蛋白1

货号:

R0142h

商标:
EIAab®
监管等级:
别名:

INCAM-100, CD106, V-CAM 1

序列号:
P19320
来源:
E.coli
种属:
Human
标签:
His
序列:
CSLTLDVQGRENNKDYFSPE
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human VCAM1 Protein
规格 & 价格: cart
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Human VCAM1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p21.2 by HGNC 1p21.2 by Entrez Gene 1p21.2 by Ensembl
VCAM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds to ECMV-D capsid proteins and acts as a receptor for this virus.


功能:
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.


亚细胞位置:
Membrane Single-pass type I membrane protein



[1].
"Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen."

[2].
"Alternative splicing of human VCAM-1 in activated vascular endothelium."

[3].
"Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis."

[4].
"Genetic susceptibility to distinct bladder cancer subphenotypes."

[5].
"Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment."

[6].
"Risk of meningioma and common variation in genes related to innate immunity."

[7].
"Identification of type 2 diabetes-associated combination of SNPs using support vector machine."

[8].
"Polymorphisms in innate immunity genes and risk of childhood leukemia."

[9].
"Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population."

[10].
"Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls."
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