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Ube2j2 (基因名), Ubiquitin-conjugating enzyme E2 J2 (蛋白名), ub2j2_mouse.
产品名称:

Mouse Ube2j2/ Ubiquitin-conjugating enzyme E2 J2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Non-canonical ubiquitin-conjugating enzyme 2, NCUBE-2, Ncube2

序列号:
Q6P073
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Mouse Ube2j2 Protein
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Mouse Ube2j2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Interacts with murid herpesvirus 4 protein K3 (mK3).


功能:
In case of infection by the murid herpesvirus 4, its association with the viral E3 ligase K3 mediates ubiquitination of host surface class I (MHC-I) H-2D(b)/H2-D1 and H-2K(b)/H2-K1 molecules before they exit the endoplasmic reticulum, leading to their degradation by the ERAD system, thus blocking the immune detection of virus-infected cells. The complex formed with the murid herpesvirus 4 protein K3 mediates ubiquitination of lysine, as well as serine and threonine residues present in the cytoplasmic tail of surface class I molecules and promotes ubiquitination of hydroxylated serine or threonine residues via ester bonds instead of the classical isopeptide linkage.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type IV membrane protein


该产品尚未在任何出版物中被引用。
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