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Trim72 (基因名), Tripartite motif-containing protein 72 (蛋白名), tri72_mouse.
产品名称:

Mouse Trim72/ Tripartite motif-containing protein 72 Recombinant Protein
基序含蛋白质72

货号:

R3671m

商标:
EIAab®
监管等级:
别名:

Mitsugumin-53, Mg53, Mg53

序列号:
Q1XH17
来源:
E.coli
种属:
Mouse
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Mouse Trim72 Protein
规格 & 价格: cart
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Mouse Trim72 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homooligomer; disulfide-linked. Interacts with DYSF and CAV3.


功能:
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.


亚细胞位置:
Cell membrane Sarcolemma Cytoplasmic vesicle membrane Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine.


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