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TOM1L1 (基因名), TOM1-like protein 1 (蛋白名), tm1l1_human.
产品名称:

Human TOM1L1/ TOM1-like protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Src-activating and signaling molecule protein, Target of Myb-like protein 1, SRCASM

序列号:
O75674
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human TOM1L1 Protein
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Human TOM1L1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 17q23.2 by HGNC 17q23.2 by Entrez Gene 17q23.2 by Ensembl
TOM1L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with FYN, GRB2 and PIK3R1 when phosphorylated. Interacts with LYN.


功能:
Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.


亚细胞位置:
Golgi apparatus Golgi stack Endosome membrane Cytoplasm Membrane Peripheral membrane protein Cytoplasmic side A small proportion is membrane-associated.


该产品尚未在任何出版物中被引用。

[1].
"Interactions of TOM1L1 with the multivesicular body sorting machinery."

[2].
"TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM."

[3].
"Decreased Srcasm expression in hyperproliferative cutaneous lesions."

[4].
"TOM1L1 is a Lyn substrate involved in FcepsilonRI signaling in mast cells."

[5].
"Recruitment of clathrin onto endosomes by the Tom1-Tollip complex."

[6].
"Srcasm modulates EGF and Src-kinase signaling in keratinocytes."

[7].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[8].
"Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing."
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