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Timp1 (基因名), Metalloproteinase inhibitor 1 (蛋白名), timp1_mouse.
产品名称:

Mouse Timp1/ Metalloproteinase inhibitor 1 Recombinant Protein
金属蛋白酶抑制剂1

货号:

R0552m

商标:
EIAab®
监管等级:
别名:

Collagenase inhibitor 16C8 fibroblast, Erythroid-potentiating activity, TPA-S1, TPA-induced protein, Tissue inhibitor of metalloproteinases 1, EPA, TIMP-1, Timp, Timp-1

序列号:
P12032
来源:
E.coli
种属:
Mouse
标签:
His
序列:
25-205aa
预估分子量:
19.91 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
  • Mouse Timp1 Protein
  • Mouse Timp1 Protein
  • Mouse Timp1 Protein
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Mouse Timp1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Mouse Timp1 Protein
The PCR product of mouse Timp1 gene was determined by 1% Agarose stained with EB.
Mouse Timp1 Protein
Recombinant mouse Timp1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14 (By similarity). Interacts with CD63; identified in a complex with CD63 and ITGB1.


功能:
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.


亚细胞位置:
Secreted


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