EIAab
首页  >  重组蛋白  >  Human TXN Recombinant Protein
TXN (基因名), Thioredoxin (蛋白名), thio_human.
产品名称:

Human TXN/ Thioredoxin Recombinant Protein
硫氧化还原蛋白

货号:

R0702h

商标:
EIAab®
监管等级:
别名:

ATL-derived factor, Surface-associated sulphydryl protein, ADF, SASP, Trx, TRDX, TRX, TRX1

序列号:
P10599
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Human TXN Protein
规格 & 价格: cart
×
Human TXN Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q31.3 by HGNC 9q31.3 by Entrez Gene 9q31.3 by Ensembl
TXN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. In case of infection, interacts with S.typhimurium protein slrP. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA-binding activity in a redox-dependent manner.


功能:
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).


亚细胞位置:
Nucleus Cytoplasm Secreted Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947).



[1].
Seok Kyo Seo, Hyo In Yang, Kyung Eun Lee, Hye Yeon Kim, SiHyun Cho, Young Sik Choi and Byung Seok Lee

[1].
"AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1."

[2].
"Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer."

[3].
"Human thioredoxin reactivity-structure/function relationship."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population."

[6].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[7].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[8].
"The roles of thioredoxin and thioredoxin-binding protein-2 in endometriosis."

[9].
"Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer."

[10].
"Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com