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CCT4 (基因名), T-complex protein 1 subunit delta (蛋白名), tcpd_human.
产品名称:

Human CCT4/ T-complex protein 1 subunit delta Recombinant Protein

货号:

R2541h

商标:
EIAab®
监管等级:
别名:

CCT-delta, Stimulator of TAR RNA-binding, TCP-1-delta, CCTD, SRB

序列号:
P50991
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Human CCT4 Protein
规格 & 价格: cart
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Human CCT4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2p15 by HGNC 2p15 by Entrez Gene 2p15 by Ensembl
CCT4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8. Interacts with DYX1C1.


功能:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.


亚细胞位置:
Cytoplasm Melanosome Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cytoplasm Cytoskeleton Cilium basal body Identified by mass spectrometry in melanosome fractions from stage I to stage IV.


该产品尚未在任何出版物中被引用。

[1].
"Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT."

[2].
"Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA."

[3].
"Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1."

[4].
"BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly."

[5].
"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."

[6].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."

[9].
"A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death."

[10].
"Chromosomal assignment and imprinting tests for the mouse delta subunit of the cytosolic chaperonin containing TCP-1 (Cct4) gene to proximal chromosome 11."
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