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AGXT (基因名), Serine--pyruvate aminotransferase (蛋白名), spya_human.
产品名称:

Human AGXT/ Serine--pyruvate aminotransferase Recombinant Protein
丝胺酸丙酮酸氨基转移酶SPT

货号:

R9609h

商标:
EIAab®
监管等级:
别名:

Alanine--glyoxylate aminotransferase, AGT, SPT, AGT1, SPAT

序列号:
P21549
来源:
E.coli
种属:
Human
标签:
His
序列:
129-292aa
预估分子量:
18.04 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human AGXT Protein
规格 & 价格: cart
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Human AGXT Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human AGXT Protein
Recombinant human AGXT protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 2q37.3 by HGNC 2q37.3 by Entrez Gene 2q37.3 by Ensembl
AGXT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
N/A


亚细胞位置:
Peroxisome Mitochondrion Predominantly localized in the peroxisomes. Mitochondrial mistargeting occurs in variant proteins Arg-41, Arg-47, Ile-152, Arg-170 and Thr-244 associated with the disease HP1.


该产品尚未在任何出版物中被引用。

[1].
"Selected exonic sequencing of the AGXT gene provides a genetic diagnosis in 50% of patients with primary hyperoxaluria type 1."

[2].
"AGXT gene mutations and their influence on clinical heterogeneity of type 1 primary hyperoxaluria."

[3].
"Primary hyperoxaluria type I due to a point mutation of T to C in the coding region of the serine:pyruvate aminotransferase gene."

[4].
"Characterization and chromosomal mapping of a genomic clone encoding human alanine:glyoxylate aminotransferase."

[5].
"Comprehensive mutation screening in 55 probands with type 1 primary hyperoxaluria shows feasibility of a gene-based diagnosis."

[6].
"Alanine-glyoxylate aminotransferase-deficient mice, a model for primary hyperoxaluria that responds to adenoviral gene transfer."

[7].
"Implications of genotype and enzyme phenotype in pyridoxine response of patients with type I primary hyperoxaluria."

[8].
"Evaluation of mutation screening as a first line test for the diagnosis of the primary hyperoxalurias."

[9].
"Primary hyperoxaluria type 1 in the Canary Islands: a conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferase."

[10].
"Crystal structure of alanine:glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1."
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