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IBSP (基因名), Bone sialoprotein 2 (蛋白名), sial_human.
产品名称:

Human IBSP/ Bone sialoprotein 2 Recombinant Protein
骨唾液蛋白2

货号:

R1092h

商标:
EIAab®
监管等级:
别名:

Bone sialoprotein II, Cell-binding sialoprotein, Integrin-binding sialoprotein, BSP II, BNSP

序列号:
P21815
来源:
E.coli
种属:
Human
标签:
His
序列:
218-317aa
预估分子量:
11.0 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Metabolism
  • Human IBSP Protein
  • Human IBSP Protein
  • Human IBSP Protein
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Human IBSP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human IBSP protein including hydrophilcity, hydrophobicity and antigenicity.
Human IBSP Protein
Recombinant human IBSP protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 4q22.1 by HGNC 4q22.1 by Entrez Gene 4q22.1 by Ensembl
IBSP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.


亚细胞位置:
Secreted



[1].
"Structural characterization of human recombinant and bone-derived bone sialoprotein. Functional implications for cell attachment and hydroxyapatite binding."

[2].
"Characterization of the human bone sialoprotein (BSP) gene and its promoter sequence."

[3].
"The human bone sialoprotein gene (IBSP): genomic localization and characterization."

[4].
"Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk."

[5].
"Predictive significance of bone sialoprotein and osteopontin for bone metastases in resected Chinese non-small-cell lung cancer patients: a large cohort retrospective study."

[6].
"High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men."

[7].
"New sequence variants associated with bone mineral density."

[8].
"Bone sialoprotein stimulates focal adhesion-related signaling pathways: role in migration and survival of breast and prostate cancer cells."

[9].
"Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation."

[10].
"Bone sialoprotein and its transcriptional regulatory mechanism."
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