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Uba2 (基因名), SUMO-activating enzyme subunit 2 (蛋白名), sae2_mouse.
产品名称:

Mouse Uba2/ SUMO-activating enzyme subunit 2 Recombinant Protein
sumo激活酶亚基2

货号:

R12405m

商标:
EIAab®
监管等级:
别名:

Anthracycline-associated resistance ARX, Ubiquitin-like 1-activating enzyme E1B, Ubiquitin-like modifier-activating enzyme 2, Sae2, Uble1b

序列号:
Q9Z1F9
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Uba2 Protein
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Mouse Uba2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.


功能:
The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.


亚细胞位置:
Cytoplasm Nucleus Shuttles between the cytoplasm and the nucleus, sumoylation is required either for nuclear translocation or nuclear retention.


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