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SRD5A1 (基因名), 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (蛋白名), s5a1_human.
产品名称:

Human SRD5A1/ 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Recombinant Protein
3-oxo-5-alpha-steroid-4脱氢酶1

货号:

R1531h

商标:
EIAab®
监管等级:
别名:

SR type 1, Steroid 5-alpha-reductase 1, S5AR 1

序列号:
P18405
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human SRD5A1 Protein
规格 & 价格: cart
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Human SRD5A1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 5p15.31 by HGNC 5p15.31 by Entrez Gene 5p15.31 by Ensembl
SRD5A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.


亚细胞位置:
Microsome membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk."

[2].
"Polymorphisms of steroid 5-alpha-reductase type I (SRD5A1) gene are associated to peripheral arterial disease."

[3].
"Variants in the 5alpha-reductase type 1 and type 2 genes are associated with polycystic ovary syndrome and the severity of hirsutism in affected women."

[4].
"Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers."

[5].
"Gene analysis of steroid 5 alpha-reductase 1 in hyperandrogenic women."

[6].
"Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1."

[7].
"Analysis of genetic polymorphisms of steroid 5alpha-reductase type 1 and 2 genes in Korean men with androgenetic alopecia."

[8].
"New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8."

[9].
"Characterization and chromosomal mapping of a human steroid 5 alpha-reductase gene and pseudogene and mapping of the mouse homologue."

[10].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
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