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RB1 (基因名), Retinoblastoma-associated protein (蛋白名), rb_chick.
产品名称:

Chicken RB1/ Retinoblastoma-associated protein Recombinant Protein

货号:

R15639c

商标:
EIAab®
监管等级:
别名:

p104, pRb, Rb

序列号:
Q90600
来源:
E.coli
种属:
Chicken
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Chicken RB1 Protein
规格 & 价格: cart
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Chicken RB1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with and sequesters the E2F1 transcription factor. Interacts with SUV39H1, KMT5B and KMT5C (By similarity). Interacts with, and is inhibited by fowl adenovirus 1 protein GAM-1.


功能:
Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting chromatin-modifying enzymes to promoters.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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