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RAB11B (基因名), Ras-related protein Rab-11B (蛋白名), rb11b_bovin.
产品名称:

Bovine RAB11B/ Ras-related protein Rab-11B Recombinant Protein

货号:

R5606b

商标:
EIAab®
监管等级:
序列号:
Q3MHP2
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Bovine RAB11B Protein
规格 & 价格: cart
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Bovine RAB11B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with KCNMA1 (By similarity). Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. May interact with TBC1D14. Interacts with ATP6V1E1. Interacts with PI4KB.


功能:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab plays a role in endocytic recycling, regulating apical recycling of several transmembrane proteins including cystic fibrosis transmembrane conductance regulator/CFTR, epithelial sodium channel/ENaC, potassium voltage-gated channel, and voltage-dependent L-type calcium channel. May also regulate constitutive and regulated secretion, like insulin granule exocytosis. Required for melanosome transport and release from melanocytes. Also regulates V-ATPase intracellular transport in response to extracellular acidosis.


亚细胞位置:
Recycling endosome membrane Lipid-anchor Cytoplasmic side Cytoplasmic vesicle Secretory vesicle Synaptic vesicle membrane Lipid-anchor Cytoplasmic side Cytoplasmic vesicle Phagosome membrane Lipid-anchor Cytoplasmic side Recruited to phagosomes containing S.aureus.


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