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Rab3ip (基因名), Rab-3A-interacting protein (蛋白名), rab3i_rat.
产品名称:

Rat Rab3ip/ Rab-3A-interacting protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Rabin-3, SSX2-interacting protein, Rab3A-interacting protein, Rabin3, Rabin8

序列号:
Q62739
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Rab3ip Protein
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Rat Rab3ip Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with the N-terminal region of SSX2 (By similarity). Interacts with the GDP-bound forms of RAB3A, RAB3D, RAB8A and RAB8B.


功能:
Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.


亚细胞位置:
Cytoplasm Nucleus Cytoplasm Cytoskeleton Cell projection Lamellipodium Predominantly cytoplasmic but a small proportion colocalizes with SSX2 in the nucleus. Activation of protein kinase C results in redistribution to the periphery of lamellipodia. In the cytoskeleton, localizes to cortical actin (By similarity).


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