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RAB1A (基因名), Ras-related protein Rab-1A (蛋白名), rab1a_canlf.
产品名称:

Dog RAB1A/ Ras-related protein Rab-1A Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

RAB1

序列号:
P62822
来源:
E.coli
种属:
Dog
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Dog RAB1A Protein
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Dog RAB1A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with GDI1; this promotes dissociation from membranes. Interacts with C9orf72 (By similarity). May interact with YIPF5.


功能:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.


亚细胞位置:
Golgi apparatus Endoplasmic reticulum Early endosome Cytoplasm Cytosol Membrane Melanosome Alternates between membrane-associated and cytosolic forms.


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