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PRPF3 (基因名), U4/U6 small nuclear ribonucleoprotein Prp3 (蛋白名), prpf3_human.
产品名称:

Human PRPF3/ U4/U6 small nuclear ribonucleoprotein Prp3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Pre-mRNA-splicing factor 3, U4/U6 snRNP 90 kDa protein, hPrp3, HPRP3, PRP3

序列号:
O43395
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human PRPF3 Protein
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Human PRPF3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts directly with PRPF4. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39. Interacts with SART3; the interaction is direct and recruits the deubiquitinase USP4 to PRPF3. Interacts with PRPF19. Interacts ('Lys-63'-linked polyubiquitinated) with PRPF8 (via the MPN (JAB/Mov34) domain); may stabilize the U4/U6-U5 tri-snRNP complex.


功能:
Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.


亚细胞位置:
Nucleus speckle Colocalizes with spliceosomal snRNPs.


该产品尚未在任何出版物中被引用。
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