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PROM1 (基因名), Prominin-1 (蛋白名), prom1_human.
产品名称:

Human PROM1/ Prominin-1 Recombinant Protein
Prominin-1

货号:

R1952h

商标:
EIAab®
监管等级:
别名:

Antigen AC133, Prominin-like protein 1, CD133, MSTP061, PROML1

序列号:
O43490
来源:
E.coli
种属:
Human
标签:
His
序列:
179-433aa
预估分子量:
28.05 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human PROM1 Protein
  • Human PROM1 Protein
  • Human PROM1 Protein
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Human PROM1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Human PROM1 Protein
The PCR product of human PROM1 gene was determined by 1% Agarose stained with EB.
Human PROM1 Protein
Recombinant human PROM1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Interacts with CDHR1 and with actin filaments. Interacts with NAT8 and NAT8B.


功能:
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).


亚细胞位置:
Apical cell membrane Multi-pass membrane protein Cell projection Microvillus membrane Multi-pass membrane protein Cell projection Cilium Photoreceptor outer segment Endoplasmic reticulum Endoplasmic reticulum-Golgi intermediate compartment Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine.


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