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PF4 (基因名), Platelet factor 4 (蛋白名), plf4_human.
产品名称:

Human PF4/ Platelet factor 4 Recombinant Protein
血小板因子4

货号:

R0172h

商标:
EIAab®
监管等级:
别名:

C-X-C motif chemokine 4, Iroplact, Oncostatin-A, PF-4, CXCL4, SCYB4

序列号:
P02776
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human PF4 Protein
规格 & 价格: cart
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Human PF4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q13.3 by HGNC 4q13.3 by Entrez Gene 4q13.3 by Ensembl
PF4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotetramer.


功能:
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer."

[2].
"Crystal structure of recombinant human platelet factor 4."

[3].
"Structural and functional comparison of the genes for human platelet factor 4 and PF4alt."

[4].
"Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[6].
"Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes."

[7].
"Mediators of neutrophil recruitment in human abdominal aortic aneurysms."

[8].
"Platelet factor 4 is highly upregulated in dendritic cells after severe trauma."

[9].
"Immune complexes formed following the binding of anti-platelet factor 4 (CXCL4) antibodies to CXCL4 stimulate human neutrophil activation and cell adhesion."

[10].
"Elevated platelet activation in patients with atopic dermatitis and psoriasis: increased plasma levels of beta-thromboglobulin and platelet factor 4."
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