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PLCG2 (基因名), 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (蛋白名), plcg2_human.
产品名称:

Human PLCG2/ 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 Recombinant Protein
1-磷脂酰肌醇4,5-二磷酸磷酸二酯酶-2

货号:

R10550h

商标:
EIAab®
监管等级:
别名:

Phosphoinositide phospholipase C-gamma-2, Phospholipase C-IV, Phospholipase C-gamma-2, PLC-IV, PLC-gamma-2

序列号:
P16885
来源:
E.coli
种属:
Human
标签:
His
序列:
400-600aa
预估分子量:
22.11 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
  • Human PLCG2 Protein
  • Human PLCG2 Protein
  • Human PLCG2 Protein
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Human PLCG2 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human PLCG2 Protein
The PCR product of human PLCG2 gene was determined by 1% Agarose stained with EB.
Human PLCG2 Protein
Recombinant human PLCG2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 16q24.1 by HGNC 16q24.1 by Entrez Gene 16q24.1 by Ensembl
PLCG2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts (via SH2 domain) with CSF1R (tyrosine phosphorylated).


功能:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Activation of phospholipase Cgamma2 by tyrosine phosphorylation."

[2].
"Tyrosine residues in phospholipase Cgamma 2 essential for the enzyme function in B-cell signaling."

[3].
"Mapping the gene that encodes phosphatidylinositol-specific phospholipase C-gamma 2 in the human and the mouse."

[4].
"Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib."

[5].
"Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions."
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