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PDGFD (基因名), Platelet-derived growth factor D (蛋白名), pdgfd_human.
产品名称:

Human PDGFD/ Platelet-derived growth factor D Recombinant Protein
血小板源生长因子D

货号:

R1896h

商标:
EIAab®
监管等级:
别名:

Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B, MSTP036, UNQ1899/PRO4345, PDGF-D, IEGF, SCDGFB

序列号:
Q9GZP0
来源:
E.coli
种属:
Human
标签:
His
序列:
250-370aa
预估分子量:
13.31 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human PDGFD Protein
规格 & 价格: cart
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Human PDGFD Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 11q22.3 by HGNC 11q22.3 by Entrez Gene 11q22.3 by Ensembl
PDGFD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.


功能:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.


亚细胞位置:
Secreted Released by platelets upon wounding.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning of SCDGF-B, a novel growth factor homologous to SCDGF/PDGF-C/fallotein."

[2].
"Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer."

[3].
"Platelet-derived growth factor-D expression in developing and mature human kidneys."

[4].
"Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes."

[5].
"Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project."
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