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Pclaf (基因名), PCNA-associated factor (蛋白名), paf15_mouse.
产品名称:

Mouse Pclaf/ PCNA-associated factor Recombinant Protein
增殖细胞核抗原相关因子

货号:

R8921m

商标:
EIAab®
监管等级:
别名:

HCV NS5A-transactivated protein 9 homolog, PCNA-associated factor of 15 kDa, PCNA-clamp-associated factor, PAF15, Ns5atp9, Paf

序列号:
Q9CQX4
来源:
E.coli
种属:
Mouse
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Pclaf Protein
规格 & 价格: cart
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Mouse Pclaf Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts (when monoubiquitinated at Lys-15 and Lys-24) with PCNA. Interacts with isoform 2/p33ING1b of ING1. Interacts with BRCA1.


功能:
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.


亚细胞位置:
Nucleus Cytoplasm Perinuclear region Following DNA damage, localizes to DNA damage sites. Colocalizes with centrosomes in perinuclear region.


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