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ADCYAP1R1 (基因名), Pituitary adenylate cyclase-activating polypeptide type I receptor (蛋白名), pacr_human.
产品名称:

Human ADCYAP1R1/ Pituitary adenylate cyclase-activating polypeptide type I receptor Recombinant Protein
垂体腺苷酸环化酶激活肽类型Ⅰ受体

货号:

R15100h

商标:
EIAab®
监管等级:
别名:

PACAP type I receptor

序列号:
P41586
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ADCYAP1R1 Protein
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Human ADCYAP1R1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7p14.3 by HGNC 7p14.3 by Entrez Gene 7p14.3 by Ensembl
ADCYAP1R1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts (via N-terminal extracellular domain) with ADCYAP1.


功能:
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor."

[2].
"Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7."

[3].
"Genome-wide association analysis of gender differences in major depressive disorder in the Netherlands NESDA and NTR population-based samples."

[4].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[5].
"Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP-receptor type 1 expression in rat and human placenta."

[8].
"N-terminal splice variants of the type I PACAP receptor: isolation, characterization and ligand binding/selectivity determinants."

[9].
"β-Arrestin1 and 2 differentially regulate PACAP-induced PAC1 receptor signaling and trafficking."

[10].
"Pituitary adenylate cyclase activating polypeptide (PACAP), stress, and sex hormones."
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