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ADCYAP1 (基因名), Pituitary adenylate cyclase-activating polypeptide (蛋白名), paca_human.
产品名称:

Human ADCYAP1/ Pituitary adenylate cyclase-activating polypeptide Recombinant Protein
垂体腺苷酸环化酶激活肽

货号:

R1347h

商标:
EIAab®
监管等级:
别名:

PACAP

序列号:
P18509
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ADCYAP1 Protein
规格 & 价格: cart
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Human ADCYAP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 18p11.32 by HGNC 18p11.32 by Entrez Gene 18p11.32 by Ensembl
ADCYAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with ADCYAP1R1 (via N-terminal extracellular domain).


功能:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene."

[2].
"Possible association between the pituitary adenylate cyclase-activating polypeptide (PACAP) gene and major depressive disorder."

[3].
"Sudden infant death syndrome (SIDS) in African Americans: polymorphisms in the gene encoding the stress peptide pituitary adenylate cyclase-activating polypeptide (PACAP)."

[4].
"Association analysis of the pituitary adenylate cyclase-activating polypeptide (PACAP/ADCYAP1) gene in bipolar disorder."

[5].
"Genetic variation screening and association studies of the adenylate cyclase activating polypeptide 1 (ADCYAP1) gene in patients with type 2 diabetes."

[6].
"Association analysis of the pituitary adenyl cyclase activating peptide gene (PACAP) on chromosome 18p11 with schizophrenia and bipolar disorders."

[7].
"Pituitary adenylate cyclase activating polypeptide (PACAP) with 27 residues. Conformation determined by 1H NMR and CD spectroscopies and distance geometry in 25% methanol solution."

[8].
"Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide."

[9].
"A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs."

[10].
"Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells."
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