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OXSR1 (基因名), Serine/threonine-protein kinase OSR1 (蛋白名), oxsr1_human.
产品名称:

Human OXSR1/ Serine/threonine-protein kinase OSR1 Recombinant Protein
丝氨酸/ threonine-protein激酶OSR1

货号:

R3008h

商标:
EIAab®
监管等级:
别名:

Oxidative stress-responsive 1 protein, KIAA1101, OSR1

序列号:
O95747
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human OXSR1 Protein
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Human OXSR1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 3p22.2 by HGNC 3p22.2 by Entrez Gene 3p22.2 by Ensembl
OXSR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.


功能:
Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3."

[2].
"Identification of PLSCR1 as a protein that interacts with RELT family members."

[3].
"Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1."

[4].
"Structural insights into the recognition of substrates and activators by the OSR1 kinase."

[5].
"Identification of RELT homologues that associate with RELT and are phosphorylated by OSR1."

[6].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[7].
"WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells."

[8].
"Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1."

[9].
"WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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