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DDOST (基因名), Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (蛋白名), ost48_human.
产品名称:

Human DDOST/ Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Recombinant Protein
多萜长醇二磷酸寡糖蛋白环糊精糖基转移

货号:

R2093h

商标:
EIAab®
监管等级:
别名:

OK/SW-cl.45, DDOST 48 kDa subunit, KIAA0115, OST48

序列号:
P39656
来源:
E.coli
种属:
Human
标签:
His
序列:
43-427aa
预估分子量:
42.35 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human DDOST Protein
规格 & 价格: cart
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Human DDOST Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p36.12 by HGNC 1p36.12 by Entrez Gene 1p36.12 by Ensembl
DDOST Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Component of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits. OST can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes.


功能:
Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Genome organization of human 48-kDa oligosaccharyltransferase (DDOST)."

[2].
"DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation."

[3].
"DDOST, PRKCSH and LGALS3, which encode AGE-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes."

[4].
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1."

[7].
"Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients."

[8].
"Derlin-1 promotes ubiquitylation and degradation of the epithelial Na+ channel, ENaC."

[9].
"Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex."

[10].
"Inhibition of N-glycan processing modulates the network of EDEM3 interactors."
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