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NUSAP1 (基因名), Nucleolar and spindle-associated protein 1 (蛋白名), nusap_human.
产品名称:

Human NUSAP1/ Nucleolar and spindle-associated protein 1 Recombinant Protein
核仁和主轴相关蛋白1

货号:

R0523h

商标:
EIAab®
监管等级:
别名:

BM-037, PRO0310, NuSAP, ANKT

序列号:
Q9BXS6
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human NUSAP1 Protein
规格 & 价格: cart
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Human NUSAP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 15q14 by HGNC 15q14 by Entrez Gene 15q14 by Ensembl
NUSAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with DNA and microtubules. Microtubule bundling is inhibited by IPO7, KPNA2 and KPNB1 while association with DNA is also inhibited by IPO7 and KPNA2.


功能:
Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.


亚细胞位置:
Cytoplasm Nucleus Nucleolus Cytoplasm Cytoskeleton Spindle Chromosome Found in the cytoplasm and nucleolus during interphase and redistributes to the mitotic spindle in prometaphase (By similarity). Localizes to the mitotic spindle during anaphase and telophase then disappears from around the chromosomes during cytokinesis (By similarity). Localizes to multiple distinct regions of chromosomes throughout mitosis.


该产品尚未在任何出版物中被引用。

[1].
"NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization."

[2].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[3].
"High NUSAP1 expression predicts poor prognosis in colon cancer."

[4].
"NUSAP1 promotes invasion and metastasis of prostate cancer."

[5].
"Architecture of the human interactome defines protein communities and disease networks."

[6].
"Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation."

[7].
"Nucleolar and spindle associated protein 1 promotes the aggressiveness of astrocytoma by activating the Hedgehog signaling pathway."

[8].
"NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity."

[9].
"NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force."

[10].
"Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators."
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