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NOSIP (基因名), Nitric oxide synthase-interacting protein (蛋白名), nosip_bovin.
产品名称:

Bovine NOSIP/ Nitric oxide synthase-interacting protein Recombinant Protein

货号:

R8788b

商标:
EIAab®
监管等级:
别名:

E3 ubiquitin-protein ligase NOSIP, RING-type E3 ubiquitin transferase NOSIP

序列号:
Q3SWY5
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Bovine NOSIP Protein
规格 & 价格: cart
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Bovine NOSIP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with NOS1 and NOS3 (By similarity). Interacts with PP2A holoenzyme, containing PPP2CA, PPP2CB, PPP2R1A and PPP2R2A subunits.


功能:
E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.


亚细胞位置:
Cytoplasm Nucleus Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.


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