首页 > 重组蛋白 > Rat Nos2 Recombinant Protein

Nos2 (基因名), Nitric oxide synthase, inducible (蛋白名), nos2_rat.

产品名称:

Rat Nos2/ Nitric oxide synthase, inducible Recombinant Protein
诱导型一氧化氮合酶

货号:

R0837r

商标:

EIAab^®

监管等级:

RUO

别名:

Inducible NO synthase, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Inducible NOS

序列号:

Q06518

来源:

E.coli

种属:

Rat

标签:

His

序列:

991-1147aa

预估分子量:

17.27 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

关注

Rat Nos2 Protein

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 21 )
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

Recombinant rat Nos2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

通用注释

亚单元:

Homodimer. Binds SLC9A3R1 (By similarity). Interacts with GAPDH. Interacts with S100A8 and S100A9 to form the iNOS-S100A8/9 transnitrosylase complex.

功能:

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.

亚细胞位置:

N/A

数据库链接

UniGene:

Rn.10400

STRING:

10116.ENSRNOP00000067662

KEGG:

rno:24599

Pfam:

PF00667

Uniprot:

Q06518

相关产品

Human NOS2 ELISA Kit

Mouse Nos2 ELISA Kit

Bovine NOS2 ELISA Kit

Chicken NOS2 ELISA Kit

Pig NOS2 ELISA Kit

序列长度:

1147

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1147:

NLSEEQVEDY | FFQLKSQKRY | HEDIFGAVFS | YGAKKGNTLE | EPKGTRL

3D 模型:

3D 结构:

免疫原序列:

验证序列:

[1].

"Synergistic effect of cranberry extract and losartan against aluminium chloride-induced hepatorenal damage associated cardiomyopathy in rats"

S M Galal, H F Hasan, M K Abdel-Rafei, et al.

From: Archives of Physiology and Biochemistry

[2].

"Montelukast abrogates prednisolone-induced hepatic injury in rats: Modulation of mitochondrial dysfunction, oxidative/nitrosative stress, and apoptosis"

I I Hegab, H E El-Horany, M M. Elbatsh, et al.

From: Journal of Biochemical and Molecular Toxicology

[3].

"Beta-caryophyllene protects against diet-induced dyslipidemia and vascular inflammation in rats: Involvement of CB2 and PPAR-γ receptors"

D A. Youssef, H M. El-Fayoumi, M F. Mahmoud.

From: Chemico-Biological Interactions

[4].

"The anti-Alzheimer effect of telmisartan in a hyperglycemic ovariectomized rat model; role of central angiotensin and estrogen receptors"

A M. Abo-Youssef, W A. Khallaf, M M. Khattab, et al.

From: Food and Chemical Toxicology

[5].

"Bradykinin‐potentiating factor isolated from Leiurus quinquestriatus scorpion venom alleviates cardiomyopathy in irradiated rats via remodelling of the RAAS pathway"

H F Hasan, R R. Radwan, S M Galal.

From: Clinical and Experimental Pharmacology and Physiology

[6].

"Mechanistic exploration of the activities of poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid against hepatocellular carcinoma at cellular and molecular levels"

P Kumar, A K Gautam, U Kumar, et al.

From: Archives of Physiology and Biochemistry

[7].

"Assessment of hyaluronic acid-modified imatinib mesylate cubosomes through CD44 targeted drug delivery in NDEA-induced hepatic carcinoma"

R Nisha, P Kumar, U Kumar, et al.

From: International Journal of Pharmaceutics

[8].

"Protective effect of l-ascorbic acid on nickel induced pulmonary nitrosative stress in male albino rats"

SH Hattiwale, S Saha, SM Yendigeri, et al.

From: BioMetalsBioMetals

[9].

"Temporal determination of lung NO system and COX-2 upregulation following ischemia-reperfusion injury"

D Oleg, E Amar, S Shapira,et al.

From: Experimental lung research

[10].

"Neuroprotective effects of vildagliptin in rat rotenone Parkinson’s disease model: role of RAGE-NFκB and Nrf2-antioxidant signaling ..."

RM Abdelsalam, MM Safar

From: Journal of Neurochemistry

[11].

"Molecular mechanisms of the protective role of wheat germ oil against cyclosporin A-induced hepatotoxicity in rats"

ES Akool

From: Pharmaceutical Biology

[12].

"Protective effects of rosuvastatin in a rat model of lung contusion: Stimulation of the cyclooxygenase 2–prostaglandin E-2 pathway"

O Dolkart, E Amar, S Shapira, et al.

From: Surgery

[13].

"Molecular Mechanisms of the Modulatory Effect of Vitamin E on Tacrolimus (FK506)-Induced Renal Injury in Rats"

H Afify, AAH Abdel-Aziz, MN El-Din, et al.

From: British Journal of Pharmaceutical Research

[14].

"Comparative pharmaceutical study on colon targeted micro-particles of celecoxib: in-vitro–in-vivo evaluation"

Bazan L, Bendas E R, El Gazayerly O N, et al.

From: Drug delivery

[15].

"Effect of Pneumoperitoneum on Oxidative Stress and Inflammation via the Arginase Pathway in Rats"

Shin S, Na S, Kim O S, et al.

From: Yonsei medical journal

[16].

"Mangiferin mitigates gastric ulcer in ischemia/reperfused rats: involvement of PPAR-γ, NF-κB and Nrf2/HO-1 signaling pathways"

Mahmoud-Awny M, Attia A S, Abd-Ellah M F, et al.

From: PloS one

[17].

"The anti-osteoporotic and anti-atherogenic effects of alendronate and simvastatin in ovariectomized rats fed high fat diet: A comparative study of com"

MT Mohamed, S A. Abuelezz, SS Atalla, et al.

From: Biomedicine & Pharmacotherapy

[18].

"Protective effect of cardamonin against acetic acid-induced ulcerative colitis in rats"

AA Ali, ENAA Haleem, SA Khaleel, et al.

From: Pharmacological Reports

[19].

"Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling"

Shawqi H. A, Ezzeldin S. E, Marwa M. S, et al.

From: Molecular Neurobiology

[20].

"Beta-caryophyllene alleviates diet-induced neurobehavioral changes in rats: The role of CB2 and PPAR-γ receptors"

D A. Youssef, H M. El-Fayoumi, M F. Mahmoud.

From: Biomedicine & Pharmacotherapy

[21].

"Perindopril ameliorates experimental Alzheimer’s disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling"

B A. S. Messiha, M R. A. Ali, M M. Khattab, et al.

From: Inflammopharmacology

[1].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定大鼠诱导型一氧化氮合酶(Nos2)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

大鼠诱导型一氧化氮合酶(Nos2)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

反馈墙

评论数 : 0

所有用户