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MYOF (基因名), Myoferlin (蛋白名), myof_human.
产品名称:

Human MYOF/ Myoferlin Recombinant Protein
Myoferlin蛋白

货号:

R2725h

商标:
EIAab®
监管等级:
别名:

Fer-1-like protein 3, FER1L3, KIAA1207

序列号:
Q9NZM1
来源:
E.coli
种属:
Human
标签:
His
序列:
345-458aa
预估分子量:
12.54 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MYOF Protein
规格 & 价格: cart
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Human MYOF Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q23.33 by HGNC 10q23.33 by Entrez Gene 10q23.33 by Ensembl
MYOF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with DNM2 and KDR. Interacts with EHD1 (By similarity). Interacts with EHD2; the interaction is direct. Interacts with FAM65B (PubMed:24687993).


功能:
Calcium/phospholipid-binding protein that plays a role in the plasmalemma repair mechanism of endothelial cells that permits rapid resealing of membranes disrupted by mechanical stress. Involved in endocytic recycling. Implicated in VEGF signal transduction by regulating the levels of the receptor KDR.


亚细胞位置:
Cell membrane Single-pass type II membrane protein Nucleus membrane Single-pass type II membrane protein Cytoplasmic vesicle membrane Single-pass type II membrane protein Concentrated at the membrane sites of both myoblast-myoblast and myoblast-myotube fusions. Detected at the plasmalemma in endothelial cells lining intact blood vessels (By similarity). Found at nuclear and plasma membranes. Enriched in undifferentiated myoblasts near the plasma membrane in puncate structures.


该产品尚未在任何出版物中被引用。

[1].
"Myoferlin, a candidate gene and potential modifier of muscular dystrophy."

[2].
"The third human FER-1-like protein is highly similar to dysferlin."

[3].
"Solution structure of the inner DysF domain of myoferlin and implications for limb girdle muscular dystrophy type 2b."

[4].
"The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion."

[5].
"Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function."
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