首页 > 重组蛋白 > Human MUC16 Recombinant Protein

MUC16 (基因名), Mucin-16 (蛋白名), muc16_human.

产品名称:

Human MUC16/ Mucin-16 Recombinant Protein
Mucin-16

货号:

R0154h

商标:

EIAab^®

监管等级:

RUO

别名:

Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125, CA-125, MUC-16, CA125

序列号:

Q8WXI7

来源:

E.coli

种属:

Human

标签:

His

序列:

4743-4953

预估分子量:

23.21 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

关注

Human MUC16 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 19p13.2 by HGNC 19p13.2 by Entrez Gene 19p13.2 by Ensembl

MUC16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN.

功能:

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Secreted Extracellular space May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.

数据库链接

UniGene:

Hs.432676

SMR:

Q8WXI7

STRING:

9606.ENSP00000381008

KEGG:

hsa:94025

MIM:

606154

Pfam:

PF01390

Uniprot:

Q8WXI7

相关产品

Human MUC16 ELISA Kit

Human MUC16 CLIA Kit

Human MUC16 Polyclonal Antibody

Human MUC16 Monoclonal Antibody

Human MUC16

序列长度:

14507

序列:

仅供参考，详细请咨询（services@eiaab.com）

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3D 模型:

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免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Introducing the MUC16 gene: implications for prevention and early detection in epithelial ovarian cancer."

(PMID: 15788735)

[2].

"Characterization of the oligosaccharides associated with the human ovarian tumor marker CA125."

(PMID: 12734200)

[3].

"Molecular cloning of the CA125 ovarian cancer antigen: identification as a new mucin, MUC16."

(PMID: 11369781)

[4].

"MUC16 expression and risk of adenocarcinoma metastases to peritoneum, pleura, leptomeninges, and brain."

(PMID: 20090516)

[5].

"Heart failure in patients with aortic stenosis: clinical and prognostic significance of carbohydrate antigen 125 and brain natriuretic peptide measurement."

(PMID: 17662495)

[1].

人Mucin-16(MUC16)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人Mucin-16(MUC16)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人Mucin-16(MUC16)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人Mucin-16(MUC16)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人Mucin-16(MUC16)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人Mucin-16(MUC16)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人Mucin-16(MUC16)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人Mucin-16(MUC16)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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