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MINPP1 (基因名), Multiple inositol polyphosphate phosphatase 1 (蛋白名), minp1_human.
产品名称:

Human MINPP1/ Multiple inositol polyphosphate phosphatase 1 Recombinant Protein
多磷酸肌醇磷酸酶1

货号:

R12906h

商标:
EIAab®
监管等级:
别名:

2, 3-bisphosphoglycerate 3-phosphatase, Inositol (1, 3, 4, 5)-tetrakisphosphate 3-phosphatase, 2, 3-BPG phosphatase, Ins(1, 3, 4, 5)P(4) 3-phosphatase, UNQ900/PRO1917, MIPP

序列号:
Q9UNW1
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MINPP1 Protein
规格 & 价格: cart
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Human MINPP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q23.2 by HGNC 10q23.2 by Entrez Gene 10q23.2 by Ensembl
MINPP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.


亚细胞位置:
Endoplasmic reticulum lumen


该产品尚未在任何出版物中被引用。

[1].
"Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19."

[2].
"Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas."

[3].
"The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification."

[4].
"A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium."

[5].
"Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt."

[6].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."

[7].
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."

[8].
"The DNA sequence and comparative analysis of human chromosome 10."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
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