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MALT1 (基因名), Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (蛋白名), malt1_human.
产品名称:

Human MALT1/ Mucosa-associated lymphoid tissue lymphoma translocation protein 1 Recombinant Protein
粘膜相关淋巴组织淋巴瘤易位蛋白1

货号:

R15461h

商标:
EIAab®
监管等级:
别名:

MALT lymphoma-associated translocation, Paracaspase, MLT

序列号:
Q9UDY8
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human MALT1 Protein
规格 & 价格: cart
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Human MALT1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 18q21.32 by HGNC 18q21.32 by Entrez Gene 18q21.32 by Ensembl
MALT1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Binds through its Ig-like domains to BCL10. Forms oligomers which bind to TRAF6.


功能:
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.


亚细胞位置:
Cytoplasm Perinuclear region Nucleus Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.


该产品尚未在任何出版物中被引用。

[1].
"Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma."

[2].
"The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas."

[3].
"A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue."

[4].
"Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma."

[5].
"MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10."

[6].
"Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma."

[7].
"The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas."

[8].
"A novel gene, MALT1 at 18q21, is involved in t(11;18) (q21;q21) found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue."

[9].
"Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma."

[10].
"MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10."
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