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Jhdm1d (基因名), Lysine-specific demethylase 7 (蛋白名), kdm7_mouse.
产品名称:

Mouse Jhdm1d/ Lysine-specific demethylase 7 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

JmjC domain-containing histone demethylation protein 1D, Kdm7, Kiaa1718

序列号:
Q3UWM4
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Jhdm1d Protein
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Mouse Jhdm1d Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
N/A


功能:
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4K20Me1 only when nucleosome is used as a substrate and when not histone octamer is used as substrate.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
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