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Kcnip1 (基因名), Kv channel-interacting protein 1 (蛋白名), kcip1_mouse.
产品名称:

Mouse Kcnip1/ Kv channel-interacting protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

A-type potassium channel modulatory protein 1, Potassium channel-interacting protein 1, KChIP1, Kchip1

序列号:
Q9JJ57
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Kcnip1 Protein
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Mouse Kcnip1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
Component of heteromultimeric potassium channels (PubMed:19713751). Identified in potassium channel complexes containing KCND1, KCND2, KCND3, KCNIP1, KCNIP2, KCNIP3, KCNIP4, DPP6 and DPP10 (PubMed:19713751). Part of a heterooctamer composed of the tetrameric channel and four KCNIP1 chains (By similarity). Interacts with KCND3 and the N-terminal domain of KCND2. Probably part of a complex consisting of KCNIP1, KCNIP2 isoform 3 and KCND2. Self-associates to form homodimers and homotetramers. Interacts with KCNIP2 isoform 3 in a calcium-dependent manner.


功能:
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND2/Kv4.2 currents (PubMed:14572458). In vitro, modulates KCND1/Kv4.1 currents (By similarity). Increases the presence of KCND2 at the cell surface.


亚细胞位置:
Cell membrane Peripheral membrane protein Cytoplasm Cell projection Dendrite


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