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CAMK2G (基因名), Calcium/calmodulin-dependent protein kinase type II subunit gamma (蛋白名), kcc2g_human.
产品名称:

Human CAMK2G/ Calcium/calmodulin-dependent protein kinase type II subunit gamma Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

CaM kinase II subunit gamma, CAMK, CAMK-II, CAMKG

序列号:
Q13555
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human CAMK2G Protein
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Human CAMK2G Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 10q22.2 by HGNC 10q22.2 by Entrez Gene 10q22.2 by Ensembl
CAMK2G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
CAMK2 is composed of 4 different chains: alpha (CAMK2A), beta (CAMK2B), gamma (CAMK2G), and delta (CAMK2D). The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 12 subunits with two hexameric rings stacked one on top of the other.


功能:
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.


亚细胞位置:
Sarcoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side


该产品尚未在任何出版物中被引用。

[1].
"Changes in the distribution of calcium calmodulin-dependent protein kinase II at the presynaptic bouton after depolarization."

[2].
"Modulation of neuronal T-type calcium channels."

[3].
"Calcium-calmodulin-dependent protein kinase II phosphorylation modulates PSD-95 binding to NMDA receptors."

[4].
"Modulation of D2R-NR2B interactions in response to cocaine."

[5].
"CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling."

[6].
"CaMK-II modulation of GABA(A) receptors expressed in HEK293, NG108-15 and rat cerebellar granule neurons."

[7].
"Molecular signaling mechanisms underlying epileptogenesis."

[8].
"Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes."

[9].
"Mitogen-activated protein kinase signaling is essential for activity-dependent dendritic protein synthesis."

[10].
"Elucidation of characteristic structural features of ligand binding sites of protein kinases: a neural network approach."
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