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Jub (基因名), Protein ajuba (蛋白名), jub_rat.
产品名称:

Rat Jub/ Protein ajuba Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
序列号:
Q5U2Z2
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Jub Protein
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Rat Jub Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with AURKA/Aurora-A during mitosis and both proteins are phosphorylated as they form a complex (By similarity). Interacts with CTNNA1/alpha-catenin and with F-actin. Interacts with LATS2 during mitosis and this complex regulates organization of the spindle apparatus through recruitment of gamma-tubulin to the centrosome (By similarity). Interacts with GRB2 and PIP5K1A (By similarity). Forms a complex with SQSTM1, PRKCZ and TRAF6 (By similarity). Interacts with SLC1A2.


功能:
Components of cellular adhesives complexes. Contribute to cell fate determination and regulate cell proliferation and differentiation. Involved in the regulation of actin cytoskeleton dynamics and cell migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays a important role in regulation of the kinase activity of AURKA/Aurora-A for mitotic commitment. Is also a component of the IL-1 signaling pathway modulating IL-1-induced NF-kappa-B activation by influencing the assembly and activity of the PRKCZ/SQSTM1/TRAF6 multiprotein signaling complex. Can functions as adapter molecules in the formation of large multiprotein complexes that form on DNA and that influence transcription.


亚细胞位置:
Cytoplasm cytoskeleton Cell membrane Cell junction Nucleus Cytoplasm cytoskeleton centrosome Shuttles between the cytoplasm and the nucleus (By similarity). Localizes on centrosomes during G2-M phase (By similarity). Preferentially co-localizes with cadherin-adhesive complexes at sites of cell-cell contacts.


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