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ITIH4 (基因名), Inter-alpha-trypsin inhibitor heavy chain H4 (蛋白名), itih4_human.
产品名称:

Human ITIH4/ Inter-alpha-trypsin inhibitor heavy chain H4 Recombinant Protein
间α胰蛋白酶抑制剂重链H4

货号:

R13558h

商标:
EIAab®
监管等级:
别名:

Inter-alpha-trypsin inhibitor family heavy chain-related protein, Plasma kallikrein sensitive glycoprotein 120, IHRP, Gp120, PRO1851, ITI heavy chain H4, IHRP, ITIHL1, PK120

序列号:
Q14624
来源:
E.coli
种属:
Human
标签:
His
序列:
681-930aa
预估分子量:
27.5 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human ITIH4 Protein
规格 & 价格: cart
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Human ITIH4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ITIH4 Protein
Recombinant human ITIH4 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p21.1 by HGNC 3p21.1 by Entrez Gene 3p21.1 by Ensembl
ITIH4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts (via C-terminus) with DNAJC1 (via SANT 2 domain); this interaction protects ITIH4 against cleavage by kallikrein in vitro.


功能:
Type II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver development or regeneration.


亚细胞位置:
Secreted



[1].
"SNP analysis of the inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene by a fluorescence-adapted SSCP method."

[2].
"Isolation and characterization of the human inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP) gene (ITIHL1)."

[3].
"cDNA and deduced amino acid sequence of human PK-120, a plasma kallikrein-sensitive glycoprotein."

[4].
"Purification and characterization of a novel glycoprotein which has significant homology to heavy chains of inter-alpha-trypsin inhibitor family from human plasma."

[5].
"Cloning and characterization of cDNA for inter-alpha-trypsin inhibitor family heavy chain-related protein (IHRP), a novel human plasma glycoprotein."

[6].
"Site-specific glycan microheterogeneity of inter-alpha-trypsin inhibitor heavy chain H4."

[7].
"Genome-wide association study identifies five new schizophrenia loci."

[8].
"Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population."

[9].
"Inter-alpha-trypsin inhibitor heavy chain 4 is a novel marker of acute ischemic stroke."

[10].
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
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