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IQSEC1 (基因名), IQ motif and SEC7 domain-containing protein 1 (蛋白名), iqec1_human.
产品名称:

Human IQSEC1/ IQ motif and SEC7 domain-containing protein 1 Recombinant Protein

货号:

R2817h

商标:
EIAab®
监管等级:
别名:

ADP-ribosylation factors guanine nucleotide-exchange protein 100, ADP-ribosylation factors guanine nucleotide-exchange protein 2, Brefeldin-resistant Arf-GEF 2 protein, BRAG2, ARFGEP100, BRAG2, KIAA0763

序列号:
Q6DN90
来源:
E.coli
种属:
Human
标签:
His
序列:
123-404aa
预估分子量:
31.02 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human IQSEC1 Protein
规格 & 价格: cart
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Human IQSEC1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human IQSEC1 Protein
Recombinant human IQSEC1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p25.2 by HGNC 3p25.2 by Entrez Gene 3p25.2 by Ensembl
IQSEC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with ARF1 and ARF6.


功能:
Guanine nucleotide exchange factor for ARF1 and ARF6 (PubMed:24058294). Guanine nucleotide exchange factor activity is enhanced by lipid binding (PubMed:24058294). Accelerates GTP binding by ARFs of all three classes. Guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.


亚细胞位置:
Cytoplasm Nucleus At steady state, may be preferentially cytosolic.


该产品尚未在任何出版物中被引用。

[1].
"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[2].
"Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms."

[3].
"The Arf6 GEF GEP100/BRAG2 regulates cell adhesion by controlling endocytosis of beta1 integrins."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"ARF-GEP(100), a guanine nucleotide-exchange protein for ADP-ribosylation factor 6."
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