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Hspa1a (基因名), Heat shock 70 kDa protein 1A (蛋白名), hsp71_rat.
产品名称:

Rat Hspa1a/ Heat shock 70 kDa protein 1A Recombinant Protein
热休克70 kDa蛋白

货号:

R0873r

商标:
EIAab®
监管等级:
别名:

Heat shock 70 kDa protein 2, HSP70-1/HSP70-2, HSP70.2, Hsp70-1, Hspa1

序列号:
P0DMW0
来源:
E.coli
种属:
Rat
标签:
His
序列:
2-641aa
预估分子量:
70.4 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Rat Hspa1a Protein
规格 & 价格: cart
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Rat Hspa1a Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Rat Hspa1a Protein
Recombinant rat Hspa1a protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IRAK1BP1, TSC2 and DNAAF2. Component of a complex composed at least of CATSPER1, CATSPERB, CATSPERG and HSPA1B (By similarity). Interacts with TERT; the interaction occurs in the absence of the RNA component, TERC, and dissociates once the TERT complex has formed (By similarity). Interacts with CHCHD3.


功能:
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.


亚细胞位置:
Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.


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