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Flnc (基因名), Filamin-C (蛋白名), flnc_mouse.
产品名称:

Mouse Flnc/ Filamin-C Recombinant Protein
细丝蛋白C

货号:

R11397m

商标:
EIAab®
监管等级:
别名:

ABP-280-like protein, ABP-L, Actin-binding-like protein, Filamin-2, Gamma-filamin, FLN-C, Abpl, Fln2

序列号:
Q8VHX6
来源:
E.coli
种属:
Mouse
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Mouse Flnc Protein
规格 & 价格: cart
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Mouse Flnc Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer; the filamin repeat 24 and the second hinge domain are important for dimer formation (By similarity). Interacts with FLNB, INPPL1, ITGB1A, KCND2, MYOT, MYOZ1 and MYOZ3. Interacts with sarcoglycans SGCD and SGCG. Interacts (via filament repeats 17-18, 20-21 and 24) with USP25 (isoform USP25m only). Interacts with FBLIM1 (By similarity). Interacts with XIRP1; this interaction is mediated by filamin 20 repeat (By similarity). Interacts with KY. Interacts with IGFN1. Interacts with MICALL2. Interacts with ANK3. Interacts with MICALL2 (By similarity). Interacts with ANK3. Interacts with SYNPO2.


功能:
Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.


亚细胞位置:
Cytoplasm Membrane Peripheral membrane protein Cytoplasm Cytoskeleton Cytoplasm Myofibril Sarcomere Z line A small amount localizes at membranes. In striated muscle cells, it predominantly localizes in myofibrillar Z lines, while a minor fraction localizes with subsarcolemme (By similarity). Targeting to developing and mature Z lines is mediated by the intradomain insert (By similarity).


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