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Fgf2 (基因名), Fibroblast growth factor 2 (蛋白名), fgf2_mouse.
产品名称:

Mouse Fgf2/ Fibroblast growth factor 2 Recombinant Protein
肝素结合生长因子2

货号:

R0551m

商标:
EIAab®
监管等级:
别名:

Basic fibroblast growth factor, Heparin-binding growth factor 2, bFGF, HBGF-2, FGF-2, Fgf-2

序列号:
P15655
来源:
E.coli
种属:
Mouse
标签:
His
序列:
10-154aa
预估分子量:
15.95 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
  • Mouse Fgf2 Protein
  • Mouse Fgf2 Protein
  • Mouse Fgf2 Protein
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Mouse Fgf2 Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Mouse Fgf2 Protein
The PCR product of mouse Fgf2 gene was determined by 1% Agarose stained with EB.
Mouse Fgf2 Protein
Recombinant mouse Fgf2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2 (By similarity). Interacts with FGFBP3 (PubMed:20851768).


功能:
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis.


亚细胞位置:
Secreted Nucleus Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).


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