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Fermt1 (基因名), Fermitin family homolog 1 (蛋白名), ferm1_mouse.
产品名称:

Mouse Fermt1/ Fermitin family homolog 1 Recombinant Protein
Fermitin家族同系物1

货号:

R14765m

商标:
EIAab®
监管等级:
别名:

Kindlin-1, Unc-112-related protein 1, Kind1, Urp1

序列号:
P59113
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Fermt1 Protein
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Mouse Fermt1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with the cytoplasmic domain of integrins ITGB1 and ITGB3.


功能:
Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites.


亚细胞位置:
Cytoplasm Cytoskeleton Cell junction Focal adhesion Cell projection Ruffle membrane Peripheral membrane protein Cytoplasmic side Colocalizes with filamentous actin. Constituent of focal adhesions (By similarity). Localized at the basal aspect of skin keratinocytes, close to the cell membrane (By similarity). Upon TGFB1 treatment, it localizes to membrane ruffles (By similarity).


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