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FARP1 (基因名), FERM, ARHGEF and pleckstrin domain-containing protein 1 (蛋白名), farp1_human.
产品名称:

Human FARP1/ FERM, ARHGEF and pleckstrin domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Chondrocyte-derived ezrin-like protein, FERM, RhoGEF and pleckstrin domain-containing protein 1, Pleckstrin homology domain-containing family C member 2, PH domain-containing family C member 2, CDEP, PLEKHC2

序列号:
Q9Y4F1
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human FARP1 Protein
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Human FARP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 13q32.2 by HGNC 13q32.2 by Entrez Gene 13q32.2 by Ensembl
FARP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with CADM1. Interacts with RAC1 (By similarity).


功能:
Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).


亚细胞位置:
Cell membrane Peripheral membrane protein Cytoplasmic side Cell junction Synapse Cell junction Synapse Synaptosome Cytoplasm Cytosol Cell projection Filopodium Cell projection Dendrite Cell projection Dendritic spine Recruited to the cell membrane via interaction with CADM1.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning and characterization of CDEP, a novel human protein containing the ezrin-like domain of the band 4.1 superfamily and the Dbl homology domain of Rho guanine nucleotide exchange factors."

[2].
"Structural basis for autoinhibition of the guanine nucleotide exchange factor FARP2."

[3].
"Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease."

[4].
"Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study."

[5].
"Voxelwise genome-wide association study (vGWAS)."
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