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Faap20 (基因名), Fanconi anemia core complex-associated protein 20 (蛋白名), fap20_mouse.
产品名称:

Mouse Faap20/ Fanconi anemia core complex-associated protein 20 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

FANCA-associated protein of 20 kDa, Fanconi anemia-associated protein of 20 kDa

序列号:
Q3UN58
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Faap20 Protein
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Mouse Faap20 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Component of the Fanconi anemia (FA) complex. Interacts with FANCA; interaction is direct. Interacts with REV1.


功能:
Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.


亚细胞位置:
Nucleus Chromosome Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8.


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