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ENOX2 (基因名), Ecto-NOX disulfide-thiol exchanger 2 (蛋白名), enox2_human.
产品名称:

Human ENOX2/ Ecto-NOX disulfide-thiol exchanger 2 Recombinant Protein
外NOx硫硫醇交换器2

货号:

R15186h

商标:
EIAab®
监管等级:
别名:

APK1 antigen, Cytosolic ovarian carcinoma antigen 1, Tumor-associated hydroquinone oxidase, tNOX, COVA1

序列号:
Q16206
来源:
E.coli
种属:
Human
标签:
His
序列:
263-366aa
预估分子量:
11.44 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human ENOX2 Protein
  • Human ENOX2 Protein
  • Human ENOX2 Protein
规格 & 价格: cart
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Human ENOX2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human ENOX2 Protein
The PCR product of human ENOX2 gene was determined by 1% Agarose stained with EB.
Human ENOX2 Protein
Recombinant human ENOX2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: Xq26.1 by HGNC Xq26.1 by Entrez Gene Xq26.1 by Ensembl
ENOX2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock.


亚细胞位置:
Cell membrane Secreted Extracellular space Extracellular and plasma membrane-associated.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface."

[2].
"Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients."

[3].
"Biochemical basis for the biological clock."

[4].
"Isolation and characterization of a tumor-associated NADH oxidase (tNOX) from the HeLa cell surface."

[5].
"Surface NADH oxidase of HeLa cells lacks intrinsic membrane binding motifs."

[6].
"The plasma membrane NADH oxidase of HeLa cells has hydroquinone oxidase activity."

[7].
"The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide-thiol oxidoreductase with protein disulfide-thiol interchange activity."

[8].
"Molecular cloning and expression of a cDNA encoding a protein detected by the K1 antibody from an ovarian carcinoma (OVCAR-3) cell line."

[9].
"Stress-induced down-regulation of tumor-associated NADH oxidase during apoptosis in transformed cells."

[10].
"RNA interference targeting tNOX attenuates cell migration via a mechanism that involves membrane association of Rac."
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