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RNASE3 (基因名), Eosinophil cationic protein (蛋白名), ecp_human.
产品名称:

Human RNASE3/ Eosinophil cationic protein Recombinant Protein
嗜酸性粒细胞阳离子蛋白

货号:

R1758h

商标:
EIAab®
监管等级:
别名:

Ribonuclease 3, RNase 3, ECP, ECP, RNS3

序列号:
P12724
来源:
E.coli
种属:
Human
标签:
His
序列:
28-160aa
预估分子量:
14.63 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human RNASE3 Protein
  • Human RNASE3 Protein
  • Human RNASE3 Protein
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Human RNASE3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Human RNASE3 Protein
The PCR product of human RNASE3 gene was determined by 1% Agarose stained with EB.
Human RNASE3 Protein
Recombinant human RNASE3 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). In vitro interacts with and insert into lipid bilayers composed of dioleoyl phosphatidylcholine and dioleoyl phosphatidylglycerol. In vitro, tends to form amyloid-like aggregates at pH 3, but not at pH 5, nor 7.


功能:
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.


亚细胞位置:
Secreted Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.


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