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Dnaja3 (基因名), DnaJ homolog subfamily A member 3, mitochondrial (蛋白名), dnja3_mouse.
产品名称:

Mouse Dnaja3/ DnaJ homolog subfamily A member 3, mitochondrial Recombinant Protein
DnaJ homolog亚家族A成员3,线粒体

货号:

R14558m

商标:
EIAab®
监管等级:
别名:

DnaJ protein Tid-1, Tumorous imaginal discs protein Tid56 homolog, mTid-1, Tid1

序列号:
Q99M87
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Mouse Dnaja3 Protein
规格 & 价格: cart
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Mouse Dnaja3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with JAK2, HSPA9B and IFN-gammaR2 chain. Interacts with Ras GTPase-activating protein 1 (RASA1). Isoform 2 interacts with MUSK (via the cytoplasmic domain).


功能:
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity (By similarity). Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.


亚细胞位置:
Mitochondrion matrix Cytoplasm Cytosol Cell junction Synapse Postsynaptic cell membrane Peripheral membrane protein Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK.


该产品尚未在任何出版物中被引用。
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