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DNASE1 (基因名), Deoxyribonuclease-1 (蛋白名), dnas1_human.
产品名称:

Human DNASE1/ Deoxyribonuclease-1 Recombinant Protein
脱氧核糖核酸酶1

货号:

R1127h

商标:
EIAab®
监管等级:
别名:

Deoxyribonuclease I, DNase I, DNL1, DRNI

序列号:
P24855
来源:
E.coli
种属:
Human
标签:
His
序列:
23-282aa
预估分子量:
28.6 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human DNASE1 Protein
规格 & 价格: cart
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Human DNASE1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16p13.3 by HGNC 16p13.3 by Entrez Gene 16p13.3 by Ensembl
DNASE1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization.


亚细胞位置:
Secreted Nucleus envelope Secretory protein, stored in zymogen granules and found in the nuclear envelope.



[1].
"Molecular analysis of HumDN1 VNTR polymorphism of the human deoxyribonuclease I in systemic lupus erythematosus."

[2].
"Gln222Arg (A2317G) polymorphism in the deoxyribonuclease I gene exhibits ethnic and functional differences."

[3].
"A novel mutation in the DNASE1 gene is related with protein instability and decreased enzyme activity in thyroid autoimmunity."

[4].
"Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation."

[5].
"Analysis of genetic polymorphism of deoxyribonuclease I in Ovambo and Turk populations using a genotyping method."
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