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首页  >  重组蛋白  >  Human CLSTN3 Recombinant Protein
CLSTN3 (基因名), Calsyntenin-3 (蛋白名), cstn3_human.
产品名称:

Human CLSTN3/ Calsyntenin-3 Recombinant Protein

货号:

R12432h

商标:
EIAab®
监管等级:
别名:

Alcadein-beta, Alc-beta, CS3, KIAA0726

序列号:
Q9BQT9
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CLSTN3 Protein
规格 & 价格: cart
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Human CLSTN3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12p13.31 by HGNC 12p13.31 by Entrez Gene 12p13.31 by Ensembl
CLSTN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Directly interacts with APBA2. Forms a tripartite complex with APBA2 and APP. Interacts with low affinity with KLC1.


功能:
May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation.


亚细胞位置:
Cell membrane Single-pass type I membrane protein Endoplasmic reticulum membrane Golgi apparatus membrane Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with both axodendritic and axospinous localization.


该产品尚未在任何出版物中被引用。

[1].
"The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns."

[2].
"Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation."

[3].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[4].
"Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism."

[5].
"Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Stabilization of intracellular trafficking and metabolism of amyloid β-protein precursor and Alcadein β by apolipoprotein E."

[8].
"Calsyntenin-3 molecular architecture and interaction with neurexin 1α."

[9].
"Proteomic analysis of podocyte exosome-enriched fraction from normal human urine."

[10].
"Calsyntenin-3 C-terminal fragment accumulates in dystrophic neurites surrounding aβ plaques in tg2576 mouse and Alzheimer disease brains: its neurotoxic role in mediating dystrophic neurite formation."
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