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CAMK2N2 (基因名), Calcium/calmodulin-dependent protein kinase II inhibitor 2 (蛋白名), ck2n2_human.
产品名称:

Human CAMK2N2/ Calcium/calmodulin-dependent protein kinase II inhibitor 2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

CaM-KII inhibitory protein, CaM-KIIN

序列号:
Q96S95
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CAMK2N2 Protein
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Human CAMK2N2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 3q27.1 by HGNC 3q27.1 by Entrez Gene 3q27.1 by Ensembl
CAMK2N2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with CAMK2A and CAMK2B in the presence of Ca(2+)/calmodulin or after autophosphorylation.


功能:
Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.


亚细胞位置:
Nucleus Cytoplasm Cytosol Excluded from nucleus when coexpressed with activated CAMK2.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning and characterization of a novel calcium/calmodulin-dependent protein kinase II inhibitor from human dendritic cells."

[2].
"Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway."

[3].
"Characterization of a calmodulin kinase II inhibitor protein in brain."

[4].
"A mega-analysis of genome-wide association studies for major depressive disorder."

[5].
"Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients."

[6].
"Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro."

[7].
"Biochemical and computational analysis of LNX1 interacting proteins."

[8].
"Differential regulation of CaMKII inhibitor beta protein expression after exposure to a novel context and during contextual fear memory formation."

[9].
"A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization."

[10].
"Dual mechanism of a natural CaMKII inhibitor."
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